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Alessandra Ottani Selected Research

2- (2- (2- (5- bromo- 2- methoxyphenyl)ethyl)- 3- fluorophenyl)- 4,5- dihydro- 1H- imidazole

6/2018Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.

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Alessandra Ottani Research Topics

Disease

10Ischemic Stroke
01/2017 - 09/2007
7Alzheimer Disease (Alzheimer's Disease)
01/2020 - 09/2013
7Myocardial Ischemia (Ischemic Heart Diseases)
12/2015 - 03/2009
7Brain Ischemia (Cerebral Ischemia)
05/2013 - 02/2004
6Ischemia
12/2015 - 02/2004
6Shock
06/2012 - 03/2009
4Stroke (Strokes)
11/2011 - 03/2009
3Neurodegenerative Diseases (Neurodegenerative Disease)
01/2017 - 03/2014
3Infarction (Infarctions)
12/2015 - 07/2010
3Pain (Aches)
11/2006 - 08/2004
2Cognitive Dysfunction
07/2015 - 10/2014
2Inflammation (Inflammations)
03/2014 - 09/2013
2Traumatic Brain Injuries (Traumatic Brain Injury)
04/2012 - 03/2012
2Reperfusion Injury
10/2011 - 01/2010
2Necrosis
02/2011 - 07/2010
2Headache (Headaches)
01/2007 - 08/2004
1Neoplasms (Cancer)
06/2018
1Glioblastoma (Glioblastoma Multiforme)
06/2018
1Amyloid Plaque
05/2017
1Memory Disorders (Memory Loss)
05/2017
1Spinal Cord Injuries (Spinal Cord Injury)
01/2017
1Traumatic Subarachnoid Hemorrhage
01/2017
1Brain Injuries (Brain Injury)
01/2017
1Heart Arrest (Cardiac Arrest)
12/2014
1Acidosis
12/2014
1Dementia (Dementias)
03/2014
1Myocardial Infarction
06/2013
1Hypotension (Low Blood Pressure)
06/2012
1Osteosarcoma (Osteogenic Sarcoma)
03/2012
1Hemorrhagic Shock
03/2012
1Hemorrhage
03/2012
1Pancreatitis
05/2011
1Multiple Organ Failure (MODS)
02/2011

Drug/Important Bio-Agent (IBA)

21MelanocortinsIBA
06/2018 - 09/2007
10Melanocyte-Stimulating Hormones (MSH)IBA
12/2015 - 01/2010
8Peptides (Polypeptides)IBA
12/2015 - 09/2007
6Type 4 Melanocortin Receptor (Melanocortin-4 Receptor)IBA
01/2017 - 05/2011
6Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
12/2015 - 07/2010
6Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2013 - 02/2010
5Proteins (Proteins, Gene)FDA Link
01/2020 - 02/2010
5Phosphotransferases (Kinase)IBA
09/2013 - 07/2010
4Caspase 3 (Caspase-3)IBA
09/2013 - 07/2010
3Interleukin-10 (Interleukin 10)IBA
12/2014 - 02/2011
3Adrenocorticotropic Hormone (ACTH)FDA Link
06/2013 - 01/2010
3Neuroprotective AgentsIBA
03/2012 - 03/2009
3Cholinergic Agents (Cholinergics)IBA
10/2011 - 03/2009
34-Nle-7-Phe-alpha- MSHIBA
07/2010 - 03/2009
3alpha-MSHIBA
07/2010 - 03/2009
3Analgesics (Analgesic Drugs)IBA
01/2007 - 08/2004
2Hydrogen Sulfide (Sulfide, Hydrogen)IBA
01/2019 - 09/2013
2Pharmaceutical PreparationsIBA
06/2018 - 01/2007
2tau Proteins (tau Protein)IBA
05/2017 - 09/2013
2Amyloid (Amyloid Fibrils)IBA
05/2017 - 03/2014
2Janus KinasesIBA
12/2015 - 12/2014
2Interleukin-6 (Interleukin 6)IBA
12/2014 - 03/2012
2Epinephrine (Adrenaline)FDA LinkGeneric
12/2014 - 06/2012
2Bromodeoxyuridine (BrdU)IBA
05/2013 - 10/2011
2Chlorisondamine (Chlorisondamine Chloride)IBA
05/2011 - 02/2011
2Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
05/2011 - 02/2011
2Messenger RNA (mRNA)IBA
02/2011 - 02/2010
2Endothelin-1 (Endothelin 1)IBA
03/2009 - 09/2007
2Acetaminophen (Paracetamol)FDA LinkGeneric
11/2006 - 02/2006
2Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
02/2004 - 10/2003
1Therapeutic UsesIBA
01/2020
1Amyloidogenic ProteinsIBA
01/2020
1Temozolomide (Temodar)FDA LinkGeneric
06/2018
12- (2- (2- (5- bromo- 2- methoxyphenyl)ethyl)- 3- fluorophenyl)- 4,5- dihydro- 1H- imidazoleIBA
06/2018
1flavocoxidIBA
05/2017
1InflammasomesIBA
05/2017
1EicosanoidsIBA
05/2017
1Hemeproteins (Heme Protein)IBA
12/2015
1Potassium ChlorideFDA LinkGeneric
12/2014
1Biomarkers (Surrogate Marker)IBA
03/2014
1alpha- cyano- (3,4- dihydroxy)- N- benzylcinnamideIBA
06/2013
1U 0126 (UO 126)IBA
06/2013
1Cosyntropin (Cortrosyn)FDA LinkGeneric
06/2013
1EnzymesIBA
06/2013
1Transcription Factors (Transcription Factor)IBA
06/2013
1Apoptosis Regulatory ProteinsIBA
06/2013
1Heme Oxygenase-1IBA
06/2013
1CateninsIBA
05/2013
1Norepinephrine (Noradrenaline)FDA LinkGeneric
06/2012
1LeptinIBA
06/2012
1Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA
03/2012
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2012
1Activating Transcription Factor 3IBA
03/2012
1CeruletideIBA
05/2011
1butir-His-Phe-Arg-Trp-Sar-NH2IBA
05/2011
1salicylhydroxamic acid (SHAM)IBA
02/2011
1LipopolysaccharidesIBA
02/2011
1ZymosanIBA
02/2011

Therapy/Procedure

3Ligation
12/2015 - 07/2010
2Heart Transplantation (Grafting, Heart)
04/2012 - 01/2010
2Intraperitoneal Injections
05/2011 - 02/2011
2Treatment Delay
08/2009 - 09/2007
1Cardiopulmonary Resuscitation (CPR)
12/2014
1Aftercare (After-Treatment)
09/2013
1General Anesthesia
03/2012
1Vagotomy
05/2011
1Injections
05/2011